+ |
GSK3B | down-regulates quantity by destabilization
phosphorylation
|
ZNF322 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264891 |
Ser391 |
SEKGLELsPPHASEA |
Homo sapiens |
NCI-H1299 Cell |
pmid |
sentence |
28581525 |
CK1delta and GSK3beta kinases sequentially phosphorylate ZNF322A at serine-396 and then serine-391. Moreover, the doubly phosphorylated ZNF322A protein creates a destruction motif for the ubiquitin ligase FBXW7alpha leading to ZNF322A protein destruction. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CSNK1D | down-regulates quantity by destabilization
phosphorylation
|
ZNF322 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264892 |
Ser396 |
ELSPPHAsEASQMS |
Homo sapiens |
NCI-H1299 Cell |
pmid |
sentence |
28581525 |
CK1delta and GSK3beta kinases sequentially phosphorylate ZNF322A at serine-396 and then serine-391. Moreover, the doubly phosphorylated ZNF322A protein creates a destruction motif for the ubiquitin ligase FBXW7alpha leading to ZNF322A protein destruction. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FBXW7 | down-regulates quantity by destabilization
ubiquitination
|
ZNF322 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264898 |
|
|
Homo sapiens |
NCI-H1299 Cell |
pmid |
sentence |
28581525 |
CK1delta and GSK3beta kinases sequentially phosphorylate ZNF322A at serine-396 and then serine-391. Moreover, the doubly phosphorylated ZNF322A protein creates a destruction motif for the ubiquitin ligase FBXW7alpha leading to ZNF322A protein destruction. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ZNF322 | up-regulates quantity by expression
transcriptional regulation
|
POU5F1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264900 |
|
|
Mus musculus |
|
pmid |
sentence |
24550733 |
Chromatin immunoprecipitation (ChIP) and dual-luciferase reporter assays revealed that Zfp322a binds to Pou5f1 and Nanog promoters and regulates their transcription. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
ZNF322 | up-regulates quantity by expression
transcriptional regulation
|
NANOG |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264899 |
|
|
Mus musculus |
|
pmid |
sentence |
24550733 |
Chromatin immunoprecipitation (ChIP) and dual-luciferase reporter assays revealed that Zfp322a binds to Pou5f1 and Nanog promoters and regulates their transcription. |
|
Publications: |
1 |
Organism: |
Mus Musculus |