| + |
DRAM2 | up-regulates quantity by expression 
transcriptional regulation
|
ROCK1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259144 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). Furthermore, DRAM2 overexpression increased the expression of proteins RAC1, RHOA, RHOC, ROCK1, and decreased RHOB expression, all of which are cell migration factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DRAM2 | up-regulates quantity by expression
transcriptional regulation
|
RHOA |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259142 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). Furthermore, DRAM2 overexpression increased the expression of proteins RAC1, RHOA, RHOC, ROCK1, and decreased RHOB expression, all of which are cell migration factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DRAM2 | down-regulates quantity by repression 
transcriptional regulation
|
CDKN1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259147 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
DRAM2 plays an oncogenic role in NSCLC via regulating p53 expression. Knockdown of DRAM2 caused an increase of p53 and p21 expression, and overexpression of p53 caused a decrease of DRAM2 expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DRAM2 | down-regulates quantity by repression
transcriptional regulation
|
RHOB |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259145 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). Furthermore, DRAM2 overexpression increased the expression of proteins RAC1, RHOA, RHOC, ROCK1, and decreased RHOB expression, all of which are cell migration factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DRAM2 | down-regulates quantity by repression
transcriptional regulation
|
TP53 |
0.312 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259146 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
DRAM2 plays an oncogenic role in NSCLC via regulating p53 expression. Knockdown of DRAM2 caused an increase of p53 and p21 expression, and overexpression of p53 caused a decrease of DRAM2 expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DRAM2 | up-regulates quantity by expression
transcriptional regulation
|
RAC1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259141 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). Furthermore, DRAM2 overexpression increased the expression of proteins RAC1, RHOA, RHOC, ROCK1, and decreased RHOB expression, all of which are cell migration factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DRAM2 | up-regulates quantity by expression
transcriptional regulation
|
RHOC |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259143 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). Furthermore, DRAM2 overexpression increased the expression of proteins RAC1, RHOA, RHOC, ROCK1, and decreased RHOB expression, all of which are cell migration factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TP53 | down-regulates quantity by repression
transcriptional regulation
|
DRAM2 |
0.312 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259148 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30755245 |
DRAM2 plays an oncogenic role in NSCLC via regulating p53 expression. Knockdown of DRAM2 caused an increase of p53 and p21 expression, and overexpression of p53 caused a decrease of DRAM2 expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
DRAM2
- 
- 