Summary

Name SND1
Full Name Staphylococcal nuclease domain-containing protein 1
Synonyms 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator | TDRD11
Primary ID Q7KZF4
Links - -
Type protein
Relations 6
Function Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:28546213, PubMed:18453631). As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213). Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934). Plays a role in PIM1 regulation of MYB activity (PubMed:9809063). Functions as a transcriptional coactivator for STAT5 (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ SND1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation IGFBP3 0.2
Publications: 1 Organism: Homo Sapiens
+ SND1up-regulates img/indirect-activation.png Proliferation 0.7
Publications: 1 Organism: Homo Sapiens
+ SND1down-regulates quantity by destabilization img/direct_inhibition.png binding MGLL 0.2
Publications: 1 Organism: Homo Sapiens
+ SREBF1down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation SND1 0.2
Publications: 1 Organism: Homo Sapiens
+ SND1up-regulates activity img/direct-activation.png binding STAT6 0.496
Publications: 1 Organism: In Vitro
+ SREBF2up-regulates quantity by expression img/direct-activation.png transcriptional regulation SND1 0.353
Publications: 1 Organism: Homo Sapiens