Name TTN
Full Name Titin
Synonyms Connectin, Rhabdomyosarcoma antigen MU-RMS-40.14
Primary ID Q8WZ42
Links - -
Type protein
Relations 2
Function Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.


Modifications Tables


Regulator Mechanism target score
+ img/unknown.png phosphorylation TCAP 0.33
Publications: 1 Organism: Mus Musculus
+ up-regulates img/indirect-activation.png TTN 0.08
Publications: 1 Organism: Homo Sapiens