Summary

Name RAPGEF4
Full Name Rap guanine nucleotide exchange factor 4
Synonyms Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII | CGEF2, EPAC2
Primary ID Q8WZA2
Links - -
Type protein
Relations 2
Function Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).

Viewer

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png guanine nucleotide exchange factor RAP1B 0.804
Publications: 1 Organism: Chlorocebus Aethiops
+ up-regulates activity img/direct-activation.png guanine nucleotide exchange factor RAP1A 0.786
Publications: 1 Organism: Chlorocebus Aethiops