Summary
Name | ![]() |
Full Name | Rap guanine nucleotide exchange factor 4 |
Synonyms | Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII | CGEF2, EPAC2 |
Primary ID | Q8WZA2 |
Links | ![]() ![]() ![]() |
Type | protein |
Relations | 6 |
Pathways | GLP-1 and GIP receptor signaling in PDAC |
Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Invo ... View More |
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Type: | Score: | Layout: | SPV |
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Relations
Regulator |
Mechanism |
target |
score
ℹ
|
|
---|---|---|---|---|
+ | RAPGEF4 | up-regulates quantity ![]() |
INS | 0.384 |
Publications: | 1 | Organism: | Homo Sapiens | |
+ | RAPGEF4 | up-regulates activity ![]() |
RAP1A | 0.789 |
Publications: | 1 | Organism: | Chlorocebus Aethiops | |
+ | RAPGEF4 | up-regulates activity ![]() |
RAP1B | 0.807 |
Publications: | 1 | Organism: | Chlorocebus Aethiops | |
+ | 3',5'-cyclic AMP | up-regulates activity ![]() |
RAPGEF4 | 0.8 |
Publications: | 1 | Organism: | Homo Sapiens | |
+ | RAPGEF4 | up-regulates quantity ![]() |
RAP1A | 0.789 |
Publications: | 1 | Organism: | Homo Sapiens | |
+ | RAPGEF4 | up-regulates quantity ![]() |
ABCC8 | 0.708 |
Publications: | 1 | Organism: | Homo Sapiens | |