3.0
Summary
| Name |  PIK3R3View Modifications |
| Full Name | Phosphatidylinositol 3-kinase regulatory subunit gamma |
| Synonyms | PI3-kinase regulatory subunit gamma, PI3K regulatory subunit gamma, PtdIns-3-kinase regulatory subunit gamma, Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, PI3-kinase subunit p55-gamma, PtdIns-3-kinase regulatory subunit p55-gamma, p55PIK |
| Primary ID | Q92569 |
| Links |  -  -  |
| Type | protein |
| Relations | 7 |
| Function | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | INSR |
phosphorylation
|
PIK3R3 | 0.61 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Brain, Kidney | |||
| + | PIK3R3 | up-regulates 
binding
|
PIK3CA | 0.84 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PIK3R3 | up-regulates
binding
|
PI3K | 0.73 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PLEKHG2 | up-regulates activity
binding
|
PIK3R3 | 0.252 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | ALK | up-regulates activity
phosphorylation
|
PIK3R3 | 0.363 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PIK3R3 | up-regulates activity
binding
|
TP53 | 0.301 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | IGF1R | up-regulates
binding
|
PIK3R3 | 0.804 |
| Publications: | 1 | Organism: | Homo Sapiens | |