Summary

Name PROX1
Full Name Prospero homeobox protein 1
Synonyms Homeobox prospero-like protein PROX1, PROX-1 |
Primary ID Q92786
Links - -
Type protein
Relations 5
Pathways T-Lymphocyte: IFN gamma
Function Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation IFNG 0.263
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Epithelial-mesenchymal_transition 0.7
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/indirect-activation.png HIF1A 0.261
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation PROX1 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png RORC 0.276
Publications: 1