+ |
MSI2 | down-regulates quantity by repression
transcriptional regulation
|
NUMB |
0.431 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-169848 |
|
|
Homo sapiens |
Leukemia Cell |
pmid |
sentence |
21084860 |
Msi2 was shown to be upregulated in blast crisis cml and to negatively regulate expression ofnumb. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
HOXA9 | up-regulates quantity by expression
transcriptional regulation
|
MSI2 |
0.44 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-167725 |
|
|
Homo sapiens |
|
pmid |
sentence |
20805843 |
Nup98-hoxa9 oncogene binds the putative element at 5.7 kb upstream of transcription start site to trigger the upregulated expression of musashi2 gene (b). The elevated level of musashi2 leads to the downregulation of numb, by binding to the 3' utr of numb mrna to inhibit translation |
|
Publications: |
1 |
Organism: |
Homo Sapiens |