+ |
CAMK4 | down-regulates
phosphorylation
|
PHB2 |
0.345 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-174437 |
Ser91 |
RARPRKIsSPTGSKD |
Homo sapiens |
|
pmid |
sentence |
21689744 |
Here we show that calcium/calmodulin-dependent kinase iv (camk iv) specifically binds to the c terminus of phb2 and phosphorylates phb2 at serine 91. Camk iv effectively decreased phb2-mediated repression of mef2 activity through phosphorylation |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle |
+ |
AKT1 | down-regulates
binding
|
PHB2 |
0.5 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-252541 |
|
|
Mus musculus |
|
pmid |
sentence |
15173318 |
Akt binds prohibitin 2 and relieves its repression of myod and muscle differentiation |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
PHB2 | down-regulates
binding
|
MYOD1 |
0.372 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-235843 |
|
|
Mus musculus |
C2C12 Cell |
pmid |
sentence |
15173318 |
Phb2 interacts with both myod and mef2, and represses both myod- and mef2-dependent gene transcription. Furthermore, binding of phb2 to both myod and mef2 significantly decreases upon myogenic differentiation. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
Tissue: |
Muscle |
+ |
PHB2 | down-regulates
binding
|
MEF2A |
0.314 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-235840 |
|
|
Mus musculus |
C2C12 Cell |
pmid |
sentence |
15173318 |
Phb2 interacts with both myod and mef2, and represses both myod- and mef2-dependent gene transcription. Furthermore, binding of phb2 to both myod and mef2 significantly decreases upon myogenic differentiation. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
Tissue: |
Muscle |
+ |
AKT | down-regulates
binding
|
PHB2 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-234441 |
|
|
Mus musculus |
|
pmid |
sentence |
15173318 |
Akt binds prohibitin 2 and relieves its repression of myod and muscle differentiation |
|
Publications: |
1 |
Organism: |
Mus Musculus |