4.0
Summary
| Name |  KIFC1View Modifications |
| Full Name | Kinesin-like protein KIFC1 |
| Synonyms | Kinesin-like protein 2, Kinesin-related protein HSET | HSET, KNSL2 |
| Primary ID | Q9BW19 |
| Links |  -  -  |
| Type | protein |
| Relations | 9 |
| Function | Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ATM | up-regulates quantity by stabilization 
phosphorylation
|
KIFC1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | ATR | up-regulates quantity by stabilization
phosphorylation
|
KIFC1 | 0.256 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CDK1 | up-regulates quantity by stabilization
phosphorylation
|
KIFC1 | 0.459 |
| Publications: | 1 | Organism: | In Vitro | |
| + | CyclinB/CDK1 | up-regulates quantity by stabilization
phosphorylation
|
KIFC1 | 0.423 |
| Publications: | 1 | Organism: | In Vitro | |
| + | KIFC1 | up-regulates 
|
Proliferation | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KIFC1 | up-regulates
|
Epithelial-mesenchymal_transition | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | APC-c | down-regulates quantity by destabilization 
ubiquitination
|
KIFC1 | 0.257 |
| Publications: | 1 | Organism: | In Vitro | |
| + | KIFC1 | up-regulates activity
binding
|
CENPE | 0.575 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KIFC1 | up-regulates
|
Cell_migration | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |