Summary

Name NHEJ1
Full Name Non-homologous end-joining factor 1
Synonyms Protein cernunnos, XRCC4-like factor | XLF
Primary ID Q9H9Q4
Links - -
Type protein
Relations 2
Function DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17470781). Binds DNA in a length-dependent manner (PubMed:17317666).

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation NHEJ1 0.656
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation NHEJ1 0.574
Publications: 1 Organism: Homo Sapiens