Summary

Name CDC14A
Full Name Dual specificity protein phosphatase CDC14A
Synonyms CDC14 cell division cycle 14 homolog A
Primary ID Q9UNH5
Links - -
Type protein
Relations 12
Function Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png dephosphorylation KMT5A
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png dephosphorylation IREB2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation TP53
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png dephosphorylation SIRT2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation MAPK6 0.64
Publications: 4 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png dephosphorylation MAPK6
Publications: 4 Organism: Homo Sapiens