3.0
Summary
| Name |  FIS1
|
| Full Name | Mitochondrial fission 1 protein |
| Synonyms | FIS1 homolog, hFis1, Tetratricopeptide repeat protein 11, TPR repeat protein 11 | TTC11 |
| Primary ID | Q9Y3D6 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Pathways | Mitochondrial dynamics in T cell exhaustion |
| Function | Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. |
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polyubiquitination, ubiquitination