Summary

Name PRKAB1
Full Name 5'-AMP-activated protein kinase subunit beta-1
Synonyms AMPK subunit beta-1, AMPKb | AMPK
Primary ID Q9Y478
Links - -
Type protein
Relations 8
Function Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation PRKAB1 0.923
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation NOS3 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation STIM1 0.2
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by destabilization img/direct_inhibition.png phosphorylation PROX1 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PRKAB1 0.335
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation RPTOR 0.443
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding AMPK 0.865
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation ULK1 0.516
Publications: 1 Organism: Homo Sapiens