| + |
EIF4E2 | form complex 
binding
|
EIF4E2/GIGYF2 complex |
0.713 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261008 |
|
|
Homo sapiens |
HeLa-S3 Cell |
| pmid |
sentence |
| 22751931 |
A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development|GIGYF2 interacts specifically with m4EHP. The stabilities of m4EHP and GIGYF2 proteins are coregulated. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GIGYF2 | form complex
binding
|
EIF4E2/GIGYF2 complex |
0.713 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261009 |
|
|
Homo sapiens |
HeLa-S3 Cell |
| pmid |
sentence |
| 22751931 |
A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development|GIGYF2 interacts specifically with m4EHP. The stabilities of m4EHP and GIGYF2 proteins are coregulated. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ZFP36 | up-regulates activity 
relocalization
|
EIF4E2/GIGYF2 complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261015 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30917308 |
A key factor in this regulation is tristetraprolin (TTP), an RNA-binding protein (RBP) that recruits RNA-destabilizing factors and the translation inhibitory complex 4EHP-GIGYF1/2 to AU-rich element (ARE)-containing mRNAs |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
EIF4E2/GIGYF2 complex | down-regulates 
|
Protein_synthesis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261013 |
|
|
Homo sapiens |
HeLa-S3 Cell |
| pmid |
sentence |
| 22751931 |
A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development|m4EHP and/or GIGYF2 proteins repress translation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
EIF4E2/GIGYF2 complex