| + |
CENPC | up-regulates activity 
binding
|
CENP-A nucleosome |
0.725 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263706 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20566683 |
CENP-C is required for centromere assembly. CENP-C and CENP-N bind to different sites on the same CENP-A nucleosomes. CENP-C, like CENP-N, interacts directly and specifically with CENP-A nucleosomes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
H2AC4 | form complex 
binding
|
CENP-A nucleosome |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263700 |
|
|
in vitro |
|
| pmid |
sentence |
| 23324462 |
In vitro assembly of both yeast and human CENP-A nucleosomes yields standard octameric structures containing two copies each of CENP-A, H2A, H2B and H4 histones. Human CENP-A also produces rigidified homotypic CENP-A/H4 tetramers in vitro. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
CENP-A nucleosome | up-regulates 
|
Chromatine_condensation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263703 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20566683 |
Centromeres contain specialized nucleosomes in which histone H3 is replaced by the histone variant centromere protein A (CENP-A). CENP-A nucleosomes are thought to act as an epigenetic mark that specifies centromere identity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CENP-A nucleosome | up-regulates
|
Centromere_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263704 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20566683 |
Centromeres contain specialized nucleosomes in which histone H3 is replaced by the histone variant centromere protein A (CENP-A). CENP-A nucleosomes are thought to act as an epigenetic mark that specifies centromere identity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CENPA | form complex
binding
|
CENP-A nucleosome |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263702 |
|
|
in vitro |
|
| pmid |
sentence |
| 23324462 |
In vitro assembly of both yeast and human CENP-A nucleosomes yields standard octameric structures containing two copies each of CENP-A, H2A, H2B and H4 histones. Human CENP-A also produces rigidified homotypic CENP-A/H4 tetramers in vitro. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
H4C1 | form complex
binding
|
CENP-A nucleosome |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263701 |
|
|
in vitro |
|
| pmid |
sentence |
| 23324462 |
In vitro assembly of both yeast and human CENP-A nucleosomes yields standard octameric structures containing two copies each of CENP-A, H2A, H2B and H4 histones. Human CENP-A also produces rigidified homotypic CENP-A/H4 tetramers in vitro. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
CENPN | up-regulates activity
binding
|
CENP-A nucleosome |
0.899 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263705 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20566683 |
CENP-C, like CENP-N, interacts directly and specifically with CENP-A nucleosomes. CENP-C and CENP-N bind to different sites on the same CENP-A nucleosomes. CENP-N also binds directly to CENP-A nucleosomes, thus providing additional CENP-A nucleosome contacts that reinforce the specificity of the centromere assembly process |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
H2BC11 | form complex
binding
|
CENP-A nucleosome |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263699 |
|
|
in vitro |
|
| pmid |
sentence |
| 23324462 |
In vitro assembly of both yeast and human CENP-A nucleosomes yields standard octameric structures containing two copies each of CENP-A, H2A, H2B and H4 histones. Human CENP-A also produces rigidified homotypic CENP-A/H4 tetramers in vitro. |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
CENP-A nucleosome
CPX-5647