| + |
MCU_MICUB_variant | up-regulates quantity 
relocalization
|
calcium(2+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270864 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MICU1 | form complex 
binding
|
MCU_MICUB_variant |
0.69 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270859 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SMDT1 | form complex
binding
|
MCU_MICUB_variant |
0.632 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270861 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MCUB | form complex
binding
|
MCU_MICUB_variant |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270863 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MICU2 | form complex
binding
|
MCU_MICUB_variant |
0.657 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270860 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MCU | form complex
binding
|
MCU_MICUB_variant |
0.707 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270862 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
MCU_MICUB_variant
CPX-5966