+ |
UNC5A | up-regulates
|
Chemorepulsion_of_axon |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268182 |
|
|
Homo sapiens |
|
pmid |
sentence |
30108487 |
Netrin binding to the receptor deleted in colorectal cancer (DCC) results in attractive responses, viahomodimerization of DCC (covered in detail in later sections), whereas heterodimerization between DCC and receptor uncoordinated locomotion 5 (UNC5) converts this attractive response into repulsion |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Axon guidance |
+ |
UNC5 | up-regulates
|
Chemorepulsion_of_axon |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268177 |
|
|
Homo sapiens |
|
pmid |
sentence |
30108487 |
Netrin binding to the receptor deleted in colorectal cancer (DCC) results in attractive responses, viahomodimerization of DCC (covered in detail in later sections), whereas heterodimerization between DCC and receptor uncoordinated locomotion 5 (UNC5) converts this attractive response into repulsion |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Axon guidance |
+ |
Calcineurin | up-regulates
|
Chemorepulsion_of_axon |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268386 |
|
|
Homo sapiens |
|
pmid |
sentence |
15363394 |
In this study, we have identified CaMKII and CaN-PP1 as the downstream effectors of localized Ca2+ signals in mediating attractive and repulsive turning responses of growth cones, respectively. Local Ca2+ elevation activates CaMKII and CaN-PP1 for attraction and repulsion, respectively. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Pathways: | Axon guidance, Oxytocin signaling |