Relation Results

Summary

Name Action_potential
Primary ID SIGNOR-PH82
Type phenotype
Description A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
Relations 10

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Type: Score: Layout: SPV 
0.70.70.70.70.70.70.70.70.70.7SCN10AAction_potential SCN2ASCN9ASCN5ASCN8ASCN4ASCN3ACACNA1GSCN11ASCN1A

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Relations
Regulator
Mechanism
target
score ℹ
+ SCN10Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253454 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN2Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253450 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN9Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253449 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN5Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253447 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN8Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253452 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN4Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253451 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN3Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253455 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ CACNA1Gup-regulates img/direct-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-264033 Mus musculus
pmid sentence
Adult hippocampal neurogenesis plays an important role in neuronal plasticity and maintenance in mammals. Low-threshold voltage-gated T-type calcium channels produce calcium spikes that increase fast action potentials in newborn cells in the hippocampal dentate gyrus (DG)
Publications: 1 Organism: Mus Musculus
+ SCN11Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253453 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
+ SCN1Aup-regulates img/indirect-activation.png Action_potential 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-253448 Homo sapiens
pmid sentence
The expression of voltage-gated sodium channels (NaVs) is a key feature for initiation and conduction of action potentials in excitable tissues and cells such as cardiac and skeletal muscle and neurons.
Publications: 1 Organism: Homo Sapiens
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