| + |
SRC_kinase_family | up-regulates 
|
Chemotaxis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254996 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15526160 |
The SFK family of tyrosine kinases is named after its prototypic family member c-Src. SCF-induced chemotaxis of Mo7 cells was dependent on SFK activity |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
C5AR2 | up-regulates
|
Chemotaxis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263459 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9108406 |
We report here that the anaphylatoxins C3a and C5a are chemotactic factors for the human mast cell line HMC-1, human cord blood-derived mast cells (CBMC) and cutaneous mast cells in vitro. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
C5AR1 | up-regulates
|
Chemotaxis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263460 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9108406 |
We report here that the anaphylatoxins C3a and C5a are chemotactic factors for the human mast cell line HMC-1, human cord blood-derived mast cells (CBMC) and cutaneous mast cells in vitro. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Complement Signaling |
| + |
C3AR1 | up-regulates
|
Chemotaxis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263471 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9108406 |
We report here that the anaphylatoxins C3a and C5a are chemotactic factors for the human mast cell line HMC-1, human cord blood-derived mast cells (CBMC) and cutaneous mast cells in vitro. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Complement Signaling |
| + |
ICAM1 | up-regulates
|
Chemotaxis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255042 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23994464 |
Before leaving the vessel lumen, neutrophils crawl on the endothelium, primarily using cell surface Mac-1 integrins binding to endothelial ICAM-1. After finding the place for transmigration, neutrophils migrate to the interstitium through transcellular or paracellular routes and begin chemotaxing towards the site of infection/inflammation within the perivascular and interstitial space. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PI3K | up-regulates
|
Chemotaxis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255012 |
|
|
|
|
| pmid |
sentence |
| 23994464 |
The PI3Kγ pathway (but not PLCβ2/3) is required for chemotaxis of the cells while both pathways are required for GPCR-induced superoxide release |
|
| Publications: |
1 |
3.0
Chemotaxis