| + |
IL5 | up-regulates 
binding
|
IL5RA |
0.884 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-40039 |
|
|
in vitro |
|
| pmid |
sentence |
| 8567620 |
Single chain and wt il5 also had similar binding affinity for soluble il5 receptor alpha chain, the specificity subunit of the il5 receptor, as measured kinetically with an optical biosensor. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
IL5 | up-regulates 
|
AKT1 |
0.397 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254351 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21106848 |
It has been reported that IL-5 family members and selected chemotactic factors can activate the PI3K-Akt pathway in human blood eosinophils |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Degranulation | up-regulates quantity
|
IL5 |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255346 |
|
|
Homo sapiens |
Mast Cell |
| pmid |
sentence |
| 17259966 |
The array of mediators released by human mast cells is enormous and explains how mast cells can be involved in so many different physiological and pathophysiological functions. Of particular relevance [...] cytokines, such as IL-3 -basophil recruitment and activation-, IL-5 -eosinophil recruitment and activation- and IL-13 -induction of IgE synthesis by B cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
IL5
- 
- 