Summary

Name PDHA1
Full Name Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Synonyms PDHE1-A type I | PHE1A
Primary ID P08559
Links - -
Type protein
Relations 24
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation PDHA1 0.39
Publications: 2 Organism: In Vitro
+ down-regulates img/direct_inhibition.png phosphorylation PDHA1 0.42
Publications: 1 Organism: In Vitro
+ down-regulates img/direct_inhibition.png phosphorylation PDHA1 0.39
Publications: 4 Organism: In Vitro, Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation PDHA1 0.42
Publications: 3 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png phosphorylation PDHA1 0.39
Publications: 2 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png phosphorylation PDHA1 0.37
Publications: 4 Organism: In Vitro
+ up-regulates activity img/direct-activation.png dephosphorylation PDHA1 0.2
Publications: 4 Organism: In Vitro, Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PDHA1 0.39
Publications: 3 Organism: In Vitro, Homo Sapiens
+ up-regulates activity img/direct-activation.png dephosphorylation PDHA1 0.14
Publications: 1 Organism: Homo Sapiens