Summary

Name NR2F2
Full Name COUP transcription factor 2
Synonyms COUP-TF2, Apolipoprotein A-I regulatory protein 1, ARP-1, COUP transcription factor II, COUP-TF II, Nuclear receptor subfamily 2 group F member 2 | ARP1, TFCOUP2
Primary ID P24468
Links - -
Type protein
Relations 6
Function Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development (PubMed:29478779).

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ NR2F2up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NR3C1 0.35
Publications: 1 Organism: Homo Sapiens
+ NR2F2down-regulates img/direct_inhibition.png binding MYOD1 0.382
Publications: 1 Organism: Homo Sapiens
+ NR2F2up-regulates img/direct-activation.png binding NR2F1 0.256
Publications: 1 Organism: Homo Sapiens
+ RXRBup-regulates img/direct-activation.png binding NR2F2 0.274
Publications: 1 Organism: Homo Sapiens
+ NR3C1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NR2F2 0.35
Publications: 1 Organism: Homo Sapiens
+ NR2F2up-regulates img/direct-activation.png binding RXRA 0.28
Publications: 1 Organism: Homo Sapiens