Summary

Name CTLA4
Full Name Cytotoxic T-lymphocyte protein 4
Synonyms Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4 | CD152
Primary ID P16410
Links - -
Type protein
Relations 7
Function Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CTLA4 0.31
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CTLA4 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CTLA4 0.22
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CTLA4 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation CTLA4 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation CTLA4 0.22
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding CTLA4
Publications: 1 Organism: Homo Sapiens