+ |
SP1 | up-regulates quantity by expression
transcriptional regulation
|
ENG |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255201 |
|
|
Homo sapiens |
Hepatic Stellate Cell |
pmid |
sentence |
21146604 |
In hepatic stellate cells, TGF-β1 upregulates endoglin expression most likely via the ALK5 pathway and requires the SP1 transcription factor. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ERG | up-regulates quantity by expression
transcriptional regulation
|
ENG |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253916 |
|
|
Homo sapiens |
|
pmid |
sentence |
22235125 |
It has been shown that ERG is a positive regulator of several EC-restricted genes including VE-cadherin, endoglin, and von Willebrand factor, and a negative regulator of other genes such as interleukin (IL)-8 and intercellular adhesion molecule (ICAM)-1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TGFB1 | up-regulates quantity by expression
transcriptional regulation
|
ENG |
0.699 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255202 |
|
|
Homo sapiens |
Hepatic Stellate Cell |
pmid |
sentence |
21146604 |
In hepatic stellate cells, TGF-β1 upregulates endoglin expression most likely via the ALK5 pathway and requires the SP1 transcription factor. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |