Summary

Name NFYA
Full Name Nuclear transcription factor Y subunit alpha
Synonyms CAAT box DNA-binding protein subunit A, Nuclear transcription factor Y subunit A, NF-YA
Primary ID P23511
Links - -
Type protein
Relations 11
Function Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation NFYA 0.13
Publications: 2
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation GFI1B 0.33
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CBS 0.30
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding SP1 0.23
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding NFYA 0.76
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SOX18 0.54
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PHGDH 0.70
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding NFY
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation OGG1 0.26
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation GCH1 0.24
Publications: 1 Organism: Homo Sapiens