Summary

Name CCNE1
Full Name G1/S-specific cyclin-E1
Synonyms CCNE1_HUMAN | CCNE
Primary ID P24864
Links - -
Type protein
Relations 16
Inhibitors seliciclib; 4-[[5-amino-1-[(2,6-difluorophenyl)-oxomethyl]-1,2,4-triazol-3-yl]amino]benzenesulfonamide; R547; 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-pyrazole-3-carboxamide
Function Essential for the control of the cell cycle at the G1/S (start) transition.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation CCNE1 0.54
Publications: 3 Organism: Homo Sapiens
Tissue: Breast
+ down-regulates img/direct_inhibition.png phosphorylation CCNE1 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding CDK2 0.56
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CCNE1 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CCNE1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CCNE1 0.14
Publications: 1 Organism: Homo Sapiens