3.0
Summary
| Name |  PCSK1View Modifications |
| Full Name | Neuroendocrine convertase 1 |
| Synonyms | NEC 1, Prohormone convertase 1, Proprotein convertase 1, PC1 | NEC1 |
| Primary ID | P29120 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PCSK1 | up-regulates activity 
cleavage
|
IAPP | 0.461 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PAX6 | up-regulates quantity by expression 
transcriptional regulation
|
PCSK1 | 0.344 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | MAFA | up-regulates quantity by expression
transcriptional regulation
|
PCSK1 | 0.294 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | ATF1 | up-regulates quantity by expression
transcriptional regulation
|
PCSK1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PCSK1 | up-regulates quantity
cleavage
|
Corticotropin | 0.2 |
| Publications: | 1 | |||
| + | CREB1 | up-regulates quantity by expression
transcriptional regulation
|
PCSK1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |