| + |
CSNK2A1 | up-regulates 
phosphorylation
|
MYH9 |
0.347 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-181811 |
Ser1943 |
RKGAGDGsDEEVDGK |
Homo sapiens |
|
| pmid |
sentence |
| 18971378 |
In egf-stimulated cells, the myosin-iia heavy chain is phosphorylated on the casein kinase 2 site (s1943) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-155987 |
Ser1943 |
RKGAGDGsDEEVDGK |
Homo sapiens |
Breast Cancer Cell |
| pmid |
sentence |
| 17567956 |
In egf-stimulated cells, the myosin-iia heavy chain is phosphorylated on the casein kinase 2 site (s1943) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-177818 |
Ser1943 |
RKGAGDGsDEEVDGK |
Homo sapiens |
|
| pmid |
sentence |
| 22123909 |
In egf-stimulated cells, the myosin-iia heavy chain is phosphorylated on the casein kinase 2 site (s1943) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-171907 |
Ser1943 |
RKGAGDGsDEEVDGK |
Homo sapiens |
Breast Cancer Cell |
| pmid |
sentence |
| 21316371 |
In egf-stimulated cells, the myosin-iia heavy chain is phosphorylated on the casein kinase 2 site (s1943) |
|
| Publications: |
4 |
Organism: |
Homo Sapiens |
| + |
MYH9 | up-regulates quantity by expression
transcriptional regulation
|
CTNNB1 |
0.278 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269284 |
|
|
Homo sapiens |
MGC-803 Cell |
| pmid |
sentence |
| 32685004 |
Nuclear MYH9 bound to the CTNNB1 promoter through its DNA-binding domain, and interacted with myosin light chain 9, β-actin and RNA polymerase II to promote CTNNB1 transcription, which conferred resistance to anoikis in GC cells in vitro and in vivo. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
USF1 | up-regulates quantity by expression 
transcriptional regulation
|
MYH9 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-222554 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 11467950 |
we have focused on element F of the NMHC-A gene. We have identified and characterized the factors which are capable of binding to element F. The basic helix_loop_helix leucine zipper (bHLH-LZ) proteins, TFEC-l and -s, which are alternatively spliced isoforms, TFE3, USF1, and USF2 have all been found to bind to element F with different binding activities and with different transcriptional activation potencies. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MYH9 | up-regulates activity
binding
|
RNA Polymerase II |
0.257 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269285 |
|
|
Homo sapiens |
MGC-803 Cell |
| pmid |
sentence |
| 32685004 |
Nuclear MYH9 bound to the CTNNB1 promoter through its DNA-binding domain, and interacted with myosin light chain 9, β-actin and RNA polymerase II to promote CTNNB1 transcription, which conferred resistance to anoikis in GC cells in vitro and in vivo. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
USF2 | up-regulates quantity by expression
transcriptional regulation
|
MYH9 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-222608 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 11467950 |
we have focused on element F of the NMHC-A gene. We have identified and characterized the factors which are capable of binding to element F. The basic helix_loop_helix leucine zipper (bHLH-LZ) proteins, TFEC-l and -s, which are alternatively spliced isoforms, TFE3, USF1, and USF2 have all been found to bind to element F with different binding activities and with different transcriptional activation potencies. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
S100A4 | down-regulates activity 
binding
|
MYH9 |
0.428 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269282 |
|
|
Mus musculus |
MTC-1 Cell |
| pmid |
sentence |
| 16707441 |
Our results show that S100A4 regulates cell polarization during directed motility by affecting the localization of protrusions through interactions with myosin-IIA, with S100A4 expressing cells displaying few side protrusions and extensive forward protrusions during chemotaxis compared with control cells. The mechanisms by which these antibodies and S100A4 increase protrusive activity and promote cellular motility are not well understood, but the observation that S100A4 can inhibit the actin-activated ATPase of myosin-IIA (34) suggests that S100A4 could function as a myosin-IIA inhibitor in vivo. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
DLC1 | down-regulates activity
binding
|
MYH9 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269283 |
|
|
Homo sapiens |
OC-3 Cell |
| pmid |
sentence |
| 26977077 |
Our study has shown that Dlc1 interacts with non-muscle myosin heavy chain II-A (Myh9), plectin and spectrin proteins in different multiprotein complexes. Overexpression of Dlc1 led to increased phosphorylation of Myh9 protein and activation of Rac1 GTPase. Dlc1 interacts with phosphorylated Myh9 (Ser-1943). This association of Dlc1 with S1943 phosphorylated Myh9, suggests that Dlc1 may be involved in reduced Myh9 filament stability. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TFEC | up-regulates quantity by expression
transcriptional regulation
|
MYH9 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-222551 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 11467950 |
we have focused on element F of the NMHC-A gene. We have identified and characterized the factors which are capable of binding to element F. The basic helix_loop_helix leucine zipper (bHLH-LZ) proteins, TFEC-l and -s, which are alternatively spliced isoforms, TFE3, USF1, and USF2 have all been found to bind to element F with different binding activities and with different transcriptional activation potencies. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TFE3 | up-regulates quantity by expression
transcriptional regulation
|
MYH9 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-222504 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 11467950 |
we have focused on element F of the NMHC-A gene. We have identified and characterized the factors which are capable of binding to element F. The basic helix_loop_helix leucine zipper (bHLH-LZ) proteins, TFEC-l and -s, which are alternatively spliced isoforms, TFE3, USF1, and USF2 have all been found to bind to element F with different binding activities and with different transcriptional activation potencies. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
MYH9
- 
- 