Name NR4A2
Full Name Nuclear receptor subfamily 4 group A member 2
Synonyms Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor | NOT, NURR1, TINUR
Primary ID P43354
Links - -
Type protein
Relations 4
Function Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).


Modifications Tables


Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation NR4A2 0.08
Publications: 2 Organism: Homo Sapiens
Tissue: Brain
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation NR4A2 0.08
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding NR4A2 0.08
Publications: 1 Organism: Homo Sapiens