Summary

Name PPP3CC
Full Name Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Synonyms CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform | CALNA3, CNA3
Primary ID P48454
Links - -
Type protein
Relations 34
Pathways IGF and Myogenesis
Inhibitors cyclosporin A; tacrolimus (anhydrous)
Function Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png dephosphorylation NFATC2 0.23
Publications: 15 Organism: Homo Sapiens
Pathways:IGF and Myogenesis
+ up-regulates activity img/direct-activation.png dephosphorylation KSR2 0.14
Publications: 3 Organism: Mus Musculus
+ down-regulates quantity by destabilization img/direct_inhibition.png dephosphorylation FLNA 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png dephosphorylation DNM1L 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png dephosphorylation PPP1R1A 0.14
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates activity img/direct-activation.png dephosphorylation BAD 0.22
Publications: 2 Organism: Homo Sapiens
+ img/unknown.png dephosphorylation DNM2 0.14
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation IL6 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates img/direct-activation.png relocalization, dephosphorylation NFATC2 0.23
Publications: 2 Organism: Homo Sapiens
Tissue: Skeletal Muscle
Pathways:IGF and Myogenesis
+ down-regulates img/direct_inhibition.png chemical inhibition PPP3CC 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png PPP3CC 0.14
Publications: 1 Organism: Mus Musculus
Tissue: Muscle, Skeletal Muscle, Myotube
Pathways:IGF and Myogenesis
+ up-regulates img/direct-activation.png binding PPP3CC 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:IGF and Myogenesis
+ up-regulates img/direct-activation.png relocalization NFATC1 0.34
Publications: 2 Organism: Homo Sapiens
Tissue: Skeletal Muscle, Muscle, Skeletal Muscle
+ up-regulates img/indirect-activation.png MEF2C 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Skeletal Muscle
Pathways:IGF and Myogenesis
+ down-regulates img/direct_inhibition.png chemical inhibition PPP3CC 0.14
Publications: 1 Organism: Homo Sapiens