Relation Results

Summary

Name	ATXN1 View Modifications
Full Name	Ataxin-1
Synonyms	Spinocerebellar ataxia type 1 protein \| ATX1, SCA1
Primary ID	P54253
Links	- -
Type	protein
Relations	4
Function	Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development (By similarity).

Viewer

Search Tools

Refine search:

by mechanism

by effect

by organism:

by tissue:

by cell-line

▶Modifications Tables

Relations

Regulator

Mechanism

target

score ℹ

up-regulates quantity by stabilization img/direct-activation.png

img/direct-activation.png

phosphorylation

0.42

Publications:

1

Organism:

Homo Sapiens

up-regulates quantity by stabilization img/direct-activation.png

img/direct-activation.png

phosphorylation

0.2

Publications:

1

Organism:

Homo Sapiens

down-regulates quantity by destabilization img/direct_inhibition.png

img/direct_inhibition.png

polyubiquitination

0.496

Publications:

1

Organism:

Homo Sapiens

up-regulates quantity by expression img/direct-activation.png

img/direct-activation.png

transcriptional regulation

0.351

Publications:

1

Organism:

Homo Sapiens