Summary

Name GNG2
Full Name Guanine nucleotide-binding protein G
Synonyms G gamma-I
Primary ID P59768
Links - -
Type protein
Relations 12
Pathways Neutrophils: G-protein-coupled receptor
Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ GNG2up-regulates img/direct-activation.png binding PI3K 0.422
Publications: 2 Organism: Homo Sapiens
+ SMOup-regulates img/direct-activation.png binding GNG2 0.351
Publications: 2 Organism: Homo Sapiens
+ GNB1up-regulates activity img/direct-activation.png binding GNG2 0.937
Publications: 1
+ GNG2up-regulates img/direct-activation.png binding PIK3CA 0.452
Publications: 2 Organism: Homo Sapiens
+ GNG2up-regulates img/direct-activation.png binding PLCG1 0.2
Publications: 1 Organism: Homo Sapiens
+ GNG2up-regulates activity img/indirect-activation.png SRC 0.439
Publications: 1
+ GPER1up-regulates activity img/direct-activation.png binding GNG2 0.351
Publications: 1
+ GNG2form complex img/form-complex.png binding GNB/GNG 0.937
Publications: 1 Organism: Homo Sapiens
+ GNG2up-regulates activity img/direct-activation.png binding GNB1 0.937
Publications: 1