Summary

Name VEPH1
Full Name Ventricular zone-expressed PH domain-containing protein homolog 1
Synonyms Protein melted | KIAA1692, VEPH
Primary ID Q14D04
Links - -
Type protein
Relations 7
Function Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.

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Relations

Regulator Mechanism target score ℹ
+ LATS2down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation VEPH1 0.2
Publications: 1 Organism: Homo Sapiens
+ VEPH1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation YAP1 0.2
Publications: 1 Organism: Homo Sapiens
+ VEPH1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation LATS1 0.2
Publications: 1 Organism: Homo Sapiens
+ VEPH1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation LATS2 0.2
Publications: 1 Organism: Homo Sapiens
+ VEPH1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation LATS1/2 0.2
Publications: 1 Organism: Homo Sapiens
+ LATS1/2down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation VEPH1 0.2
Publications: 1 Organism: Homo Sapiens
+ LATS1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation VEPH1 0.2
Publications: 1 Organism: Homo Sapiens