3.0
Summary
| Name |  PTPROView Modifications |
| Full Name | Receptor-type tyrosine-protein phosphatase O |
| Synonyms | R-PTP-O, Glomerular epithelial protein 1, Protein tyrosine phosphatase U2, PTP-U2, PTPase U2 | GLEPP1, PTPU2 |
| Primary ID | Q16827 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function (By similarity). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PTPRO | down-regulates activity 
dephosphorylation
|
STAT3 | 0.385 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | PTPRO | down-regulates quantity by destabilization
dephosphorylation
|
ERBB2 | 0.413 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPRO | down-regulates activity
dephosphorylation
|
SRC | 0.434 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPRO | down-regulates activity
dephosphorylation
|
LYN | 0.331 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPRO | down-regulates activity
dephosphorylation
|
VCP | 0.433 |
| Publications: | 1 | Organism: | Homo Sapiens | |