3.0
Summary
| Name |  PPM1LView Modifications |
| Full Name | Protein phosphatase 1L |
| Synonyms | Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon | PP2CE |
| Primary ID | Q5SGD2 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PPM1L | down-regulates 
dephosphorylation
|
MAP3K5 | 0.324 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Brain, Kidney | |||
| + | PPM1L | up-regulates activity 
dephosphorylation
|
CERT1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PPM1L | down-regulates activity
dephosphorylation
|
MAP3K7 | 0.604 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PPM1L | up-regulates activity
dephosphorylation
|
ERN1 | 0.315 |
| Publications: | 1 | Organism: | Homo Sapiens | |