3.0
Summary
| Name |  HACE1View Modifications |
| Full Name | E3 ubiquitin-protein ligase HACE1 |
| Synonyms | HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1 | KIAA1320 |
| Primary ID | Q8IYU2 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PAK1 | down-regulates activity 
phosphorylation
|
HACE1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HACE1 | down-regulates quantity by destabilization
ubiquitination
|
CCND1 | 0.313 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HACE1 | down-regulates quantity by destabilization
ubiquitination
|
RAC1 | 0.374 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Ub:E2 | up-regulates activity 
ubiquitination
|
HACE1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |