+ |
YY1 | down-regulates quantity by repression
transcriptional regulation
|
HOXB13 |
0.277 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254233 |
|
|
Homo sapiens |
Prostate Gland Cancer Cell |
pmid |
sentence |
19013255 |
Recruitment of HDAC4 by transcription factor YY1 represses HOXB13 to affect cell growth in AR-negative prostate cancers. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
HOXB13 | down-regulates quantity by repression
transcriptional regulation
|
AR |
0.509 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254475 |
|
|
Homo sapiens |
LNCaP Cell |
pmid |
sentence |
15604291 |
These results suggest that HOXB13 functions as an AR repressor to modulate the complex AR signaling and subsequent growth regulation of prostate cancer cells. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
HDAC4 | down-regulates quantity by repression
transcriptional regulation
|
HOXB13 |
0.265 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254232 |
|
|
Homo sapiens |
|
pmid |
sentence |
19013255 |
Recruitment of HDAC4 by transcription factor YY1 represses HOXB13 to affect cell growth in AR-negative prostate cancers. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
HOXB13 | down-regulates quantity by repression
transcriptional regulation
|
TCF4 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254476 |
|
|
Homo sapiens |
Prostate Cancer Cell Line |
pmid |
sentence |
15928669 |
In prostate cancers, HOXB13 negatively regulates beta-catenin/TCF4-mediated transactivation and subsequently inhibits cell growth. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
DNMT3B | down-regulates quantity by repression
transcriptional regulation
|
HOXB13 |
0.259 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254145 |
|
|
Homo sapiens |
Prostate Cancer Cell Line |
pmid |
sentence |
22808286 |
EZH2 recruited DNMT3b to HOXB13 promoter to form a repression complex. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EZH2 | down-regulates quantity by repression
transcriptional regulation
|
HOXB13 |
0.416 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254144 |
|
|
Homo sapiens |
Prostate Cancer Cell Line |
pmid |
sentence |
22808286 |
EZH2 recruited DNMT3b to HOXB13 promoter to form a repression complex. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |