| + |
STAT1/STAT3 | form complex 
binding
|
JAK1/STAT1/STAT3 |
0.689 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235658 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 15284024 |
Stimulation of EGFR induces Tyr701 phosphorylation of STAT1 and initiates complex formation of STAT1 and STAT3 with JAK1 and JAK2. Thereafter, the STATs translocate to the nucleus within 15 min. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
STAT1 | form complex
binding
|
STAT1/STAT3 |
0.59 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235661 |
|
|
Mus musculus |
Keratinocyte |
| pmid |
sentence |
| 15284024 |
Stimulation of EGFR induces Tyr701 phosphorylation of STAT1 and initiates complex formation of STAT1 and STAT3 with JAK1 and JAK2. Thereafter, the STATs translocate to the nucleus within 15 min. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
STAT3 | form complex
binding
|
STAT1/STAT3 |
0.59 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235664 |
|
|
Mus musculus |
Keratinocyte |
| pmid |
sentence |
| 15284024 |
Stimulation of EGFR induces Tyr701 phosphorylation of STAT1 and initiates complex formation of STAT1 and STAT3 with JAK1 and JAK2. Thereafter, the STATs translocate to the nucleus within 15 min. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
JAK2 | up-regulates activity 
phosphorylation
|
STAT1/STAT3 |
0.807 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254999 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15526160 |
Downstream of JAKs are the signal transducers and activators of transcription (STATs), which are phosphorylated by JAKs. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
STAT1/STAT3
CPX-6041