+ |
JAK2 | up-regulates activity
phosphorylation
|
STAT1/STAT3 |
0.806 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254999 |
|
|
Homo sapiens |
|
pmid |
sentence |
15526160 |
Downstream of JAKs are the signal transducers and activators of transcription (STATs), which are phosphorylated by JAKs. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
STAT3 | form complex
binding
|
STAT1/STAT3 |
0.596 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-235664 |
|
|
Mus musculus |
Keratinocyte |
pmid |
sentence |
15284024 |
Stimulation of EGFR induces Tyr701 phosphorylation of STAT1 and initiates complex formation of STAT1 and STAT3 with JAK1 and JAK2. Thereafter, the STATs translocate to the nucleus within 15 min. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
STAT1 | form complex
binding
|
STAT1/STAT3 |
0.596 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-235661 |
|
|
Mus musculus |
Keratinocyte |
pmid |
sentence |
15284024 |
Stimulation of EGFR induces Tyr701 phosphorylation of STAT1 and initiates complex formation of STAT1 and STAT3 with JAK1 and JAK2. Thereafter, the STATs translocate to the nucleus within 15 min. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
STAT1/STAT3 | form complex
binding
|
JAK1/STAT1/STAT3 |
0.741 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-235658 |
|
|
Mus musculus |
|
pmid |
sentence |
15284024 |
Stimulation of EGFR induces Tyr701 phosphorylation of STAT1 and initiates complex formation of STAT1 and STAT3 with JAK1 and JAK2. Thereafter, the STATs translocate to the nucleus within 15 min. |
|
Publications: |
1 |
Organism: |
Mus Musculus |