| + |
SNAI1 | form complex 
binding
|
SNAIL/RELA/PARP1 |
0.431 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254526 |
|
|
Homo sapiens |
Fibroblast, Mesenchymal Cell |
| pmid |
sentence |
| 22223884 |
Therefore, we conclude that the endogenous proteins PARP1, p65NF-κB and Snail1 form a ternary complex in the nuclei of cells that are actively expressing fibronectin |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PARP1 | form complex
binding
|
SNAIL/RELA/PARP1 |
0.484 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254528 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22223884 |
Therefore, we conclude that the endogenous proteins PARP1, p65NF-κB and Snail1 form a ternary complex in the nuclei of cells that are actively expressing fibronectin |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RELA | form complex
binding
|
SNAIL/RELA/PARP1 |
0.442 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254527 |
|
|
Homo sapiens |
Fibroblast, Mesenchymal Cell |
| pmid |
sentence |
| 22223884 |
Therefore, we conclude that the endogenous proteins PARP1, p65NF-κB and Snail1 form a ternary complex in the nuclei of cells that are actively expressing fibronectin |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SNAIL/RELA/PARP1 | up-regulates quantity by expression 
transcriptional regulation
|
FN1 |
0.411 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254529 |
|
|
Homo sapiens |
Fibroblast, Mesenchymal Cell |
| pmid |
sentence |
| 22223884 |
Taken together, our results indicate that Snail1, p65NF-κB and PARP1 interact to activate the expression of fibronectin and other ECM genes involved in cell movement. This mechanism is functional not only in epithelial cells undergoing EMT but also in fibroblasts. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
SNAIL/RELA/PARP1