| + |
SUZ12/EZH2 | up-regulates activity 
binding
|
YY1 |
0.723 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235574 |
|
|
Mus musculus |
C2C12 Cell, Satellite Cell |
| pmid |
sentence |
| 20887952 |
TNF-activated p38a kinase promotes the interaction between YY1 and PRC2, via threonine 372 phosphorylation of EZH2, the enzy- matic subunit of the complex, leading to the for- mation of repressive chromatin on Pax7 promoter. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
EZH2 | form complex 
binding
|
SUZ12/EZH2 |
0.96 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-146758 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16712789 |
Suz12 is a polycomb group protein that forms polycomb repressive complexes (prc2/3) together with eed and histone methyltransferase ezh2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SUZ12/EZH2 | form complex
binding
|
SUZ12/EZH2/YY1 |
0.842 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235577 |
|
|
Mus musculus |
C2C12 Cell, Satellite Cell |
| pmid |
sentence |
| 20887952 |
TNF-activated p38a kinase promotes the interaction between YY1 and PRC2, via threonine 372 phosphorylation of EZH2, the enzy- matic subunit of the complex, leading to the for- mation of repressive chromatin on Pax7 promoter. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
MAPK14 | up-regulates
phosphorylation
|
SUZ12/EZH2 |
0.381 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-217676 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21902831 |
P38 can phosphorylate the histone-lysine n-methyltransferase ezh2, the catalytic subunit of the polycomb repressive complex 2 (prc2), with phosphorylation of ezh2 necessary for prc2s association with the transcriptional repressor yy1 and subsequent chromatin remodelling. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SUZ12 | form complex
binding
|
SUZ12/EZH2 |
0.96 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-146764 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16712789 |
Suz12 is a polycomb group protein that forms polycomb repressive complexes (prc2/3) together with eed and histone methyltransferase ezh2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SUZ12/EZH2