| + |
IL10RA | up-regulates 
|
Phagocytosis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255443 |
|
|
|
|
| pmid |
sentence |
| 22933625 |
Recent findings have shown that IL-10 stimulation of macrophages isolated from skeletal muscles increases the phagocytic activity of macrophages |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255442 |
|
|
|
|
| pmid |
sentence |
| 19837374 |
Treatment of monocytes with IL-10 as compared to IL-15 resulted in a two-fold greater level of phagocytosis and binding of latex beads. In summary, IL-10, in comparison to IL-15, induces greater macrophage endocytic function |
|
| Publications: |
2 |
| + |
Phagocytosis | down-regulates quantity 
|
IL1B |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255445 |
|
|
|
Macrophage |
| pmid |
sentence |
| 22933625 |
Furthermore, phagocytosis of apoptotic neutrophils by M1 macrophages increased production of the Th2 cytokine TGFβ by the macrophages, while reducing expression of the Th1 cytokines IL-1β and TNF-α, reflecting a shift toward an M2 phenotype |
|
| Publications: |
1 |
| + |
FCAR | up-regulates
|
Phagocytosis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264861 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30766540 |
IgA-mediated immune effector responses such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, respiratory burst and cytokine release are mediated through FcalphaRI (CD89), an IgA-specific receptor that is expressed on monocytes, eosinophils, neutrophils and macrophages |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MEGF10 | up-regulates
|
Phagocytosis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265166 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28526325 |
Our results indicate that MEGF10 may be responsible for phagocytic activity targeted toward unwanted substances such as amyloid in cholinergic and glutamatergic neurons. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ABCA7 | up-regulates
|
Phagocytosis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265175 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27472885 |
Together these results indicate that ABCA7 mediates phagocytic clearance of amyloid-β in the brain, and reveal a mechanism by which loss of function of ABCA7 increases the susceptibility to AD. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Phagocytosis | up-regulates quantity
|
TGFB1 |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255444 |
|
|
|
Macrophage |
| pmid |
sentence |
| 22933625 |
Furthermore, phagocytosis of apoptotic neutrophils by M1 macrophages increased production of the Th2 cytokine TGFβ by the macrophages, while reducing expression of the Th1 cytokines IL-1β and TNF-α, reflecting a shift toward an M2 phenotype |
|
| Publications: |
1 |
| + |
Phagocytosis | down-regulates quantity
|
TNF |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255446 |
|
|
|
Macrophage |
| pmid |
sentence |
| 22933625 |
Furthermore, phagocytosis of apoptotic neutrophils by M1 macrophages increased production of the Th2 cytokine TGFβ by the macrophages, while reducing expression of the Th1 cytokines IL-1β and TNF-α, reflecting a shift toward an M2 phenotype |
|
| Publications: |
1 |
3.0
Phagocytosis