Myofiber: IGF1R

Pathway ID: SIGNOR-MyoIGF1R

Description: The stimulation of muscle growth through the activation of AKT/mTOR pathway has been well established and IGF1 is one important environmental stimulus that can enhance such a mechanism. IGF1 binds to its receptor and activates an intracellular cascade through the AKT pathway, ending with muscle cell growth.

Curated by: Alessandro Palma

11 Seed Entities

Organism:
Name Primary ID
mTORC1 SIGNOR-C3
IGF1R P08069
RPS6K SIGNOR-PF26
IGF1 P05019
IRS1 P35568
Cell_growth SIGNOR-PH33
TRIM63 Q969Q1
FOXO1 Q12778
PI3K SIGNOR-C156
AKT1 P31749
mTORC2 SIGNOR-C2