| + |
CSF2 | up-regulates 
binding
|
CSF2RA |
0.852 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-72458 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10572088 |
We have determined the nmr structure of a ligand-binding domain of the granulocyte colony-stimulating factor (g-csf) receptor comparisons between the spectra of the 15n-labelled domain with and without g-csf indicate that the major ligand-recognition site is on the fg loop just upstream of the wsxws sequence. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-49126 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9187659 |
We have determined the nmr structure of a ligand-binding domain of the granulocyte colony-stimulating factor (g-csf) receptor comparisons between the spectra of the 15n-labelled domain with and without g-csf indicate that the major ligand-recognition site is on the fg loop just upstream of the wsxws sequence. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
CSF2 | up-regulates
binding
|
CSF2RA/CSF2RB |
0.857 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255581 |
|
|
Homo sapiens |
Monocyte |
| pmid |
sentence |
| 9680354 |
GM-CSF elicits these diverse responses through the GM-CSF receptor (GMR). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Skeletal Muscle |
| + |
CSF2 | up-regulates activity
binding
|
CSF2RA |
0.852 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-249501 |
|
|
Homo sapiens |
Macrophage |
| pmid |
sentence |
| 18551128 |
The GM-CSF receptor (CSF2R) is a heterodimer composed of a specific ligand-binding subunit (CSF2Ralpha) and a common signal-transduction subunit (CSF2Rbeta) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CSF2 | up-regulates
binding
|
CSF3R |
0.586 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-31963 |
|
|
Homo sapiens |
Neutrophil |
| pmid |
sentence |
| 7691413 |
A g-csfr expression plasmid was introduced into interleukin-3 (il-3)-dependent mouse myeloid precursor fdc-p1 cells that normally do not respond to g-csf. G-csf stimulated proliferation of the transformants these results suggested that the g-csfr, but not the il-3/gm-csf receptors, transduced the neutrophilic differentiation signal into cells. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-144740 |
|
|
Homo sapiens |
Neutrophil |
| pmid |
sentence |
| 16492764 |
A g-csfr expression plasmid was introduced into interleukin-3 (il-3)-dependent mouse myeloid precursor fdc-p1 cells that normally do not respond to g-csf. G-csf stimulated proliferation of the transformants. These results suggested that the g-csfr, but not the il-3/gm-csf receptors, transduced the neutrophilic differentiation signal into cells |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
CSF2 | up-regulates quantity by expression 
transcriptional regulation
|
HBG2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251776 |
|
|
Homo sapiens |
Erythroblast |
| pmid |
sentence |
| 2479426 |
Granulocyte-macrophage colony-stimulating factor reactivates fetal hemoglobin synthesis in erythroblast clones from normal adults. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
CSF2
- 
- 