Summary

Name CYP19A1
Full Name Aromatase
Synonyms CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase | ARO1, CYAR, CYP19
Primary ID P11511
Links - -
Type protein
Relations 12
Pathways Luminal Breast Cancer
Inhibitors anastrozole; letrozole; EXEMESTANE
Function Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CYP19A1 0.03
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png small molecule catalysis estradiol
Publications: 1
Pathways:Luminal Breast Cancer
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CYP19A1 0.10
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CYP19A1 0.10
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CYP19A1 0.06
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CYP19A1 0.08
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CYP19A1 0.24
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CYP19A1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CYP19A1 0.05
Publications: 1 Organism: Homo Sapiens
Pathways:Luminal Breast Cancer
+ down-regulates img/direct_inhibition.png chemical inhibition CYP19A1
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CYP19A1
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition CYP19A1
Publications: 1 Organism: Homo Sapiens