Summary

Name TFE3
Full Name Transcription factor E3
Synonyms Class E basic helix-loop-helix protein 33, bHLHe33 | BHLHE33
Primary ID P19532
Links - -
Type protein
Relations 1
Function Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response (PubMed:2338243, PubMed:29146937, PubMed:30733432, PubMed:31672913). Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (By similarity). Involved in the cellular response to amino acid availability by acting downstream of MTOR

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MYH9 0.2
Publications: 1 Organism: Homo Sapiens