Summary

Name LIFR
Full Name Leukemia inhibitory factor receptor
Synonyms LIF receptor, LIF-R
Primary ID P42702
Links - -
Type protein
Relations 9
Pathways IL6
Function Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation LIFR 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation LIFR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding LIFR 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:IL6
+ up-regulates img/direct-activation.png binding IL6ST 0.42
Publications: 1 Organism: Homo Sapiens
Pathways:IL6
+ up-regulates img/direct-activation.png binding LIFR 0.45
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding LIFR 0.36
Publications: 1 Organism: Homo Sapiens
Pathways:IL6
+ up-regulates img/direct-activation.png binding LIFR 0.36
Publications: 1 Organism: Homo Sapiens