4.0
Summary
| Name |  PITX1View Modifications |
| Full Name | Pituitary homeobox 1 |
| Synonyms | Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1 | BFT, PTX1 |
| Primary ID | P78337 |
| Links |  -  -  |
| Type | protein |
| Relations | 8 |
| Function | Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PTPN1 | down-regulates quantity by destabilization 
dephosphorylation
|
PITX1 | 0.351 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | EGR1 | up-regulates activity 
binding
|
PITX1 | 0.502 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | DUX4 | up-regulates quantity by expression
transcriptional regulation
|
PITX1 | 0.304 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | PITX1 | up-regulates quantity by expression 
transcriptional regulation
|
LHB | 0.346 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | PITX1 | down-regulates quantity by repression 
transcriptional regulation
|
GNRH1 | 0.326 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | ABL1 | up-regulates activity
phosphorylation
|
PITX1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PITX1 | up-regulates activity
binding
|
POU1F1 | 0.46 |
| Publications: | 1 | Organism: | In Vitro | |