| + |
CDON |
binding
|
MAP3K5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235551 |
|
|
Mus musculus |
C2C12 Cell, Myoblast, HEK-293T Cell |
| pmid |
sentence |
| 22337877 |
Cdo and jlp interacted with ask1 or tak1 in 293t cells and c2c12 myoblasts |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Pathways: | P38 Signaling and Myogenesis |
| + |
CDON | up-regulates activity 
binding
|
ABL1 |
0.489 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-185762 |
|
|
Homo sapiens |
Myoblast |
| pmid |
sentence |
| 19470755 |
Abl binds a proline-rich motif in cdo via its sh3 domain, and these regions of abl and cdo are required for their promyogenic effects. Cdo is important for full abl kinase activity |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | P38 Signaling and Myogenesis |
| + |
CDON |
binding
|
MAP3K7 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-235554 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 22337877 |
Cdo and jlp interacted with ask1 or tak1 in 293t cells and c2c12 myoblasts |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Pathways: | P38 Signaling and Myogenesis |
| + |
CDON | up-regulates activity
binding
|
MAPK14 |
0.439 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-179867 |
|
|
Homo sapiens |
Myoblast |
| pmid |
sentence |
| 18678706 |
During myoblast differentiation, the promyogenic cell surface receptor cdo binds to the p38alpha/beta pathway scaffold protein jlp and, via jlp, p38alpha/beta itself |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | P38 Signaling and Myogenesis |
| + |
CDON | up-regulates activity
binding
|
SPAG9 |
0.474 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-150282 |
|
|
Homo sapiens |
Myoblast |
| pmid |
sentence |
| 17074887 |
In this study, we report that the cdo intracellular region interacts with jlp, a scaffold protein for the p38alpha/beta mapk pathway. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-179870 |
|
|
Homo sapiens |
Myoblast |
| pmid |
sentence |
| 18678706 |
During myoblast differentiation, the promyogenic cell surface receptor cdo binds to the p38alpha/beta pathway scaffold protein jlp and, via jlp, p38alpha/beta itself. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| Pathways: | P38 Signaling and Myogenesis |
| + |
CDON | form complex 
binding
|
CDON/SPAG9 |
0.474 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-150279 |
|
|
Homo sapiens |
Myoblast |
| pmid |
sentence |
| 17074887 |
In this study, we report that the cdo intracellular region interacts with jlp, a scaffold protein for the p38alpha/beta mapk pathway. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CDON | up-regulates activity
binding
|
BNIP2 |
0.483 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-179864 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18678706 |
Bnip-2 and jlp are brought together through mutual interaction with cdo. the cdo-bnip-2 interaction stimulates cdc42 activity, which in turn promotes p38alpha/beta activity and cell differentiation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | P38 Signaling and Myogenesis |
| + |
CDON | form complex
binding
|
CDON/BOC/PTCH1 |
0.552 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-209596 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 21664576 |
Secreted Hedgehog (HH) ligands signal through the canonical receptor Patched (PTCH1). However, recent studies implicate three additional HH-binding, cell-surface proteins, GAS1, CDO, and BOC, as putative coreceptors for HH ligands. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
CDH2 | up-regulates
binding
|
CDON |
0.63 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-163844 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20160094 |
We report here that n-cadherin ligation activates p38alpha/beta in myoblasts in a cdo-, bnip-2-, and jlp-dependent manner |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CDH15 | up-regulates activity
binding
|
CDON |
0.471 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-99250 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12634428 |
Cdo binds promyogenic cadherins form complexes with n- and m-cadherin. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | P38 Signaling and Myogenesis |
3.0
CDON
- 
- 