P38 Signaling and Myogenesis

Pathway ID: SIGNOR-P38_MyogenesisView in NDEx

Description: Starting from pro-myogenic stimuli such as TNFa or cell-to-cell contact and passing through the signalling cascade down to the key transcription factors involved in muscle differentiation, the pathway illustrates the main players involved in the regulation of myogenesis mediated by p38/MAPK14.

Curated by: Andrea Cerquone Perpetuini

complexity level

level 1 seed interactions
level 2 connect
level 3 first neighbors
level 4 all
level 5 PPI

33 Seed Entities

Organism:
Name Primary ID
ABL1 P00519
ADAM17 P78536
AKT1 P31749
AKT2 P31751
BNIP2 Q12982
CDC42 P60953
CDH15 P55291
CDON Q4KMG0
EZH2 Q15910
IGF1 P05019
IGF1R P08069
KHSRP Q92945
MAP2K3 P46734
MAP2K4 P45985
MAP2K6 P52564
MAP3K5 Q99683
MAP3K7 O43318
MAPK14 Q16539
MEF2A Q02078
MEF2C Q06413
MEF2D Q14814
MYOD1 P15172
MYOG P15173
P300/PCAF SIGNOR-C7
PAX7 P23759
RIPK1 Q13546
Skeletal Muscle Differentiation SIGNOR-PH1
SMARCD3 Q6STE5
SPAG9 O60271
TAB2 Q9NYJ8
TCF3 P15923
TNF P01375
TNFRSF1A P19438